
Makana Therapeutics Discovers Fourth Gene to Reduce Pig Organ Rejection in Humans
Key Highlights
- Makana Therapeutics discovers a fourth gene in pigs that will reduce organ rejection in human transplants.
- The fourth gene knockout builds upon their existing Triple Knockout Pig (TKO) technology.
- Clinical trials in xenotransplantation are planned for early 2026 pending FDA approval.
- Research collaboration with the University of Miami advanced this discovery.
Source: Business Wire
Notable Quotes
“ We have discovered an additional human immune system response responsible for early xenograft organ failure. ”
Joe Tector, MD, PhD, FACS, Founder at Makana
“ Our sole focus is to restore an entirely normal life to every patient with organ failure. ”
Mark Platt, CEO at Makana Therapeutics